تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Doping with anabolic androgenic steroids (AAS): Adverse effects on non-reproductive organs and functions
Doping with anabolic androgenic steroids (AAS): Adverse effects on non-reproductive organs and functions
 
لغة الوثيقة : الانجليزية 
المستخلص : Since the 1970s anabolic androgenic steroids (AAS) have been abused at ever increasing rates in competitive athletics, in recreational sports and in bodybuilding. Exceedingly high doses are often consumed over long periods, in particular by bodybuilders, causing acute or chronic adverse side effects frequently complicated by additional polypharmacy. This review summarizes side effects on non-reproductive organs and functions; effects on male and female reproduction have been recently reviewed in a parallel paper. Among the most striking AAS side effects are increases in haematocrit and coagulation causing thromboembolism, intracardiac thrombosis and stroke as well as other cardiac disturbances including arrhythmias, cardiomyopathies and possibly sudden death. 17α-alkylated AAS are liver toxic leading to cholestasis, peliosis, adenomas and carcinomas. Hyperbilirubinaemia can cause cholemic nephrosis and kidney failure. AAS abuse may induce exaggerated self-confidence, reckless behavior, aggressiveness and psychotic symptoms. AAS withdrawal may be accompanied by depression and suicidal intentions. Since AAS abuse is not or only reluctantly admitted physicians should be aware of the multitude of serious side effects when confronted with unclear symptoms. 
ردمد : 1573-2606 
اسم الدورية : Rev Endocr Metab Disord 
المجلد : 16 
العدد : 3 
سنة النشر : 1436 هـ
2015 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Tuesday, April 26, 2016 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
Eberhard NieschlagNieschlag, Eberhard باحث رئيسي eberhard.nieschlag@ukmuenster.de
Elena VoronaVorona, Elena باحث مشارك  

الملفات

اسم الملفالنوعالوصف
 38696.pdf pdf 

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